Jinan Shenghe Chemical Co., Ltd. Amifostin

Amifostin

High-quality Organiske kemikalier supplied by Jinan Shenghe Chemical Co., Ltd. Competitive pricing, reliable delivery, and full technical support for B2B buyers worldwide.

CAS: 20537-88-6 Organiske kemikalier Non-hazardous / General Chemical
ISO & Quality Controlled COA / MSDS / TDS Custom Packaging Fast Dispatch 3-5 Days
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Detailed Chemical Properties & Synonyms

Synonyms amifostineEthiofosGammaphosEthyolApaetpAminopropylaminoethyl thiophosphateEthiofos AnhydrousAmifostine AnhydrousAmifostinaWR 2721AmifostinumS-(2-((3-Aminopropyl)amino)ethyl) dihydrogen phosphorothioate

Direct from the manufacturer. Jinan Shenghe Chemical Co., Ltd. supplies this product under ISO-controlled quality with full COA / MSDS / TDS documentation and flexible OEM packaging for global B2B buyers.

Amifostin · CAS 20537-88-6 · leveret af Jinan Shenghe Chemical Co., Ltd.

Beskrivelse

Amifostine · CAS 20537-88-6 · C5H15N2O3PS. UNII ILA426L95O. Opløselighed: 1000; Opløselighed: 1.87e+01 g/L; Opløselighed: 95% Ethanol < 0.01 (mg/mL).

Identifikation

CAS registreringsnummer 20537-88-6
PubChem CID 2141
Molekylær formel C5H15N2O3PS
IUPAC navn 2-(3-aminopropylamino)ethylsulfanylphosphonic acid
UNII (FDA) ILA426L95O

Beregnet deskriptorer

Molekylvægt 214.23
XLogP3 -4.5
Antal brintbonddonorer 4
Antal brintbindingsacceptorer 6
Roterbar Bond Count 7
Præcis masse 214.05410052
Monoisotopisk masse 214.05410052
Topologisk polar overfladeareal 121
Tunge atomer 12
Formel sigtelse 0

Fysiske og kemiske egenskaber

Opløselighed 1000
Opløselighed 1.87e+01 g/L
Opløselighed 95% Ethanol < 0.01 (mg/mL)
Opløselighed Chloroform < 0.01 (mg/mL)
Opløselighed Toluene < 0.01 (mg/mL)
LogP -1.9

Fysisk beskrivelse og håndteringsnotater

  • Solid
  • White crystalline powder
  • Freely soluble in water
  • Water approximately 450 (mg/mL)
  • 146,9 Å2 [M+H]+ [CCS Type: TW; Metode: kalibreret med polyalanin og lægemiddelstandarder]
  • White solid from methanol/ether. Mp 160-161 °C (dec). /Monohydrate/

GHS-fareklassificering

Indberettede faresætninger H302 (100%)

H302 (100%): Farlig ved indtagelse [Advarsel Akut toksicitet, oral]

P264, P270, P301+P317, P330 og P501 (klik på hver P-kode for at se erklæringen)

Dokumenterede anvendelser

  • For at reducere den kumulative nyretoksicitet forbundet med gentagen administration af cisplatin hos patienter med fremskreden ovariecancer … reducere forekomsten af ​​moderat til svær xerostomi hos patienter, der gennemgår postoperativ strålebehandling for hoved- og halscancer
  • THERAP CAT: Radioprotective agent
  • Preparation: J.R. Piper, T.P. Johnston, US 3892824 (1975 to Southern Research Institute)
  • 1,3-propandiamin monoalkyleres med 2-chlorethanol til dannelse af 2-[3-(aminopropyl)amino]ethanol, og den frie OH omdannes til Br ved anvendelse af HBr. Behandling af det resulterende alkylbromid med natriumthiophosphat efterfulgt af syrning giver produktet.
  • Til reduktion af den kumulative nyretoksicitet hos patienter med ovariecancer (ved brug af cisplatin) og moderat til svær xerostomi hos patienter, der gennemgår postoperativ strålebehandling for hoved- og halscancer.
  • Amifostin er godkendt til at forhindre:

Synonymer

amifostine; 20537-88-6; Ethiofos; Gammaphos; Ethyol; Apaetp; Aminopropylaminoethyl thiophosphate; Ethiofos Anhydrous; Amifostine Anhydrous; YM-08310; Amifostina; NSC-296961; WR 2721; WR-2721; DTXSID8022585; NSC296961

Ofte stillede spørgsmål

Hvad er CAS-tallet og molekylformlen for Amifostine?

CAS 20537-88-6; molecular formula C5H15N2O3PS; molecular weight — g/mol.

Hvilke andre navne er Amifostine kendt under?

amifostine, 20537-88-6, Ethiofos, Gammaphos, Ethyol, Apaetp.

Er Amifostine klassificeret som farligt?

Rapporterede faresætninger: H302.

Hvad er de vigtigste fysiske egenskaber ved Amifostine?

Opløselighed: 1000; Opløselighed: 1.87e+01 g/L; Opløselighed: 95% Ethanol < 0.01 (mg/mL); Opløselighed: Chloroform < 0.01 (mg/mL).

Fakta på denne side er hentet fra PubChem (US National Library of Medicine) og Wikidata. Klassespecifikke data – assay, fugt, partikelstørrelse, emballage, holdbarhed – udstedes pr. batch på COA og offentliggøres ikke her.

Anvendelsesområder

Amifostin (CAS 20537-88-6, formel C5H15N2O3PS, molmasse 214.23 g/mol) anvendes i kemisk syntese, fine chemicals og beslægtede industrielle processer. For specifikation, COA og volumenpriser på Amifostin, kontakt venligst vores salgsteam.

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Packaging & Shipping

  • Standard: 25 kg fiber drum / 200 kg steel drum with double PE liner
  • Small pack: 1 kg / 5 kg aluminum foil bag for lab & sample
  • Custom: packaging size and labeling per customer requirement
  • Lead time: in-stock items ship within 3-5 business days
  • Documents: COA, MSDS / SDS, TDS provided with every shipment
  • Global: air, sea (FCL / LCL) and express to 80+ countries

Storage & Handling

Store in a cool, dry, well-ventilated place away from heat, direct sunlight and incompatible materials. Keep container tightly closed. Use appropriate personal protective equipment and refer to the SDS for full safety guidance before handling.

Frequently Asked Questions

Can you provide a Certificate of Analysis (COA) and sample?

Yes. A batch-specific COA and free or charged sample are available on request before bulk ordering.

Do you support custom synthesis or specific specifications?

Yes. We offer custom grade, particle size and purity adjustment based on your application and order volume.

What are your minimum order quantities (MOQ)?

MOQ depends on the product; small quantities are supported for R&D and trial runs.

How do you ensure consistent quality?

Every batch is tested in-house and retains full traceability from raw material to finished goods.

Why Choose Jinan Shenghe Chemical

13+
Years of Export
Serving global B2B buyers across the chemical industry since 2013.
Full Range
Products in Catalog
Broad coverage of fine chemicals, additives and intermediates.
80+
Countries Served
Reliable long-term supply with worldwide logistics.
100%
Batch Tested
COA and traceability for every shipment.

Request a Quote

Looking for pricing, availability or technical data for Amifostin?

Email us at sales@shenghechemical.com or use the button above. Our team typically responds within 1 business day.

About Jinan Shenghe Chemical Co., Ltd.

Jinan Shenghe Chemical Co., Ltd.

We are a professional chemical supplier based in Jinan, China. Since 2013, we have been connecting manufacturers and global B2B buyers with reliable sourcing, quality-controlled products and efficient logistics.

Our business covers food & feed additives, fine chemicals, pharmaceutical intermediates, eco-materials, coatings and specialty chemicals — all non-hazardous and compliant with our licensed scope.

Company Name
Jinan Shenghe Chemical Co., Ltd.
Business Type
Manufacturer Representative / Trading Company
Location
Jinan, Shandong, China
Main Products
Fine Chemicals, Additives, Intermediates
Export Markets
Asia, Europe, North & South America, Middle East
Documents Supplied
COA, MSDS / SDS, TDS
Email
sales@shenghechemical.com
Phone / WhatsApp
+86-18553102138
Tel (Office)
0531-84992235
Website
www.shenghechemical.com

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