Nebivolol
High-quality Organiske kemikalier supplied by Jinan Shenghe Chemical Co., Ltd. Competitive pricing, reliable delivery, and full technical support for B2B buyers worldwide.
Specifications
| Molecular Formula | C22H25F2NO4 |
|---|---|
| Molecular Weight | 405.435 |
| Boiling Point | 600.5°C at 760 mmHg |
| Flash Point | 316.9°C |
| Vapor Pressure | 2.88E-15mmHg at 25°C |
Detailed Chemical Properties & Synonyms
Direct from the manufacturer. Jinan Shenghe Chemical Co., Ltd. supplies this product under ISO-controlled quality with full COA / MSDS / TDS documentation and flexible OEM packaging for global B2B buyers.
Nebivolol · CAS 99200-09-6 · leveret af Jinan Shenghe Chemical Co., Ltd.
Beskrivelse
Nebivolol · CAS 99200-09-6 · C22H25F2NO4. UNII 030Y90569U. Smeltepunkt: 223.0-228.0; Opløselighed: 0.091g/100mL; Opløselighed: 4.03e-02 g/L.
Identifikation
| CAS registreringsnummer | 99200-09-6 |
|---|---|
| PubChem CID | 71301 |
| Molekylær formel | C22H25F2NO4 |
| IUPAC navn | 1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol |
| UNII (FDA) | 030Y90569U |
Beregnet deskriptorer
| Molekylvægt | 405.4 |
|---|---|
| XLogP3 | 3 |
| Antal brintbonddonorer | 3 |
| Antal brintbindingsacceptorer | 7 |
| Roterbar Bond Count | 6 |
| Præcis masse | 405.17516460 |
| Monoisotopisk masse | 405.17516460 |
| Topologisk polar overfladeareal | 71 |
| Tunge atomer | 29 |
| Formel sigtelse | 0 |
Fysiske og kemiske egenskaber
| Smeltepunkt | 223.0-228.0 |
|---|---|
| Opløselighed | 0.091g/100mL |
| Opløselighed | 4.03e-02 g/L |
| LogP | 4.183 |
| LogP | 2.76 |
| Dissociationskonstanter | 8.22 |
| Dissociationskonstanter | 8.13 |
Fysisk beskrivelse og håndteringsnotater
- Solid
GHS-fareklassificering
| Indberettede faresætninger | H302 (100%), H315 (50%), H319 (50%), H332 (50%), H335 (50%), H361 (50%) |
|---|
H302 (100%): Farlig ved indtagelse [Advarsel Akut toksicitet, oral]
H315 (50%): Forårsager hudirritation [Advarsel Hudætsning/-irritation]
Dokumenterede anvendelser
- Use (kg; approx.) in Germany (2009): >750
- Consumption (g per capita; approx.) in Germany (2009): 0.00916
- Nebivolol er indiceret til behandling af hypertension.
- Nebivolol er en FDA-godkendt medicin, der bruges til at behandle hypertension. Betablokkere er en klasse af midler, der bruges til at behandle flere tilstande, herunder hypertension, angina, arytmier, angst, hyperthyroidisme, migræneforebyggelse og forebyggelse af essentielle rystelser. American College of Cardiology (ACC)/American Heart Association (AHA) retningslinjer fraråder at bruge β-blokkere som førstelinjebehandling af hypertension og at reservere dem til patienter med komorbiditeter såsom iskæmisk hjertesygdom.
- Nebivolol er en beta-blokker og antihypertensiv medicin, der har yderligere vasodilatorisk aktivitet medieret af nitrogenoxidfrigivelse. Nebivolol er endnu ikke forbundet med tilfælde af klinisk tilsyneladende leverskade.
- Breast Feeding; Lactation; Milk, Human; Adrenergic beta-Antagonists; Antihypertensive Agents; Vasodilator Agents
Synonymer
Nebivolol; Narbivolol; 118457-14-0; R-65824; dl-Nebivolol; DTXSID9040556; R65,824; Nebivololum; nebibolol; Hypoloc; Hydrochloride, Nebivolol; RefChem:56585; alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro)-2H-1-benzopyran-2-methanol; DTXCID7020556; CHEBI:64022; C07AB12
Ofte stillede spørgsmål
Hvad er CAS-tallet og molekylformlen for Nebivolol?
CAS 99200-09-6; molecular formula C22H25F2NO4; molecular weight — g/mol.
Hvilke andre navne er Nebivolol kendt under?
Nebivolol, Narbivolol, 118457-14-0, R-65824, dl-Nebivolol, DTXSID9040556.
Er Nebivolol klassificeret som farligt?
Rapporterede faresætninger: H302, H315, H319, H332, H335.
Hvad er de vigtigste fysiske egenskaber ved Nebivolol?
Smeltepunkt: 223.0-228.0; Opløselighed: 0.091g/100mL; Opløselighed: 4.03e-02 g/L; LogP: 4.183.
Fakta på denne side er hentet fra PubChem (US National Library of Medicine) og Wikidata. Klassespecifikke data – assay, fugt, partikelstørrelse, emballage, holdbarhed – udstedes pr. batch på COA og offentliggøres ikke her.
Anvendelsesområder
Typiske anvendelsesområder for Nebivolol (CAS-nr. 99200-09-6; formel C22H25F2NO4; 405.4 g/mol) er kemisk syntese, fine chemicals og beslægtede industrielle processer. Vores salgsteam besvarer gerne forespørgsler om specifikation, COA og store mængder af Nebivolol.
Lignende produkter i samme kategori
Packaging & Shipping
- Standard: 25 kg fiber drum / 200 kg steel drum with double PE liner
- Small pack: 1 kg / 5 kg aluminum foil bag for lab & sample
- Custom: packaging size and labeling per customer requirement
- Lead time: in-stock items ship within 3-5 business days
- Documents: COA, MSDS / SDS, TDS provided with every shipment
- Global: air, sea (FCL / LCL) and express to 80+ countries
Storage & Handling
Store in a cool, dry, well-ventilated place away from heat, direct sunlight and incompatible materials. Keep container tightly closed. Use appropriate personal protective equipment and refer to the SDS for full safety guidance before handling.
Frequently Asked Questions
Yes. A batch-specific COA and free or charged sample are available on request before bulk ordering.
Yes. We offer custom grade, particle size and purity adjustment based on your application and order volume.
MOQ depends on the product; small quantities are supported for R&D and trial runs.
Every batch is tested in-house and retains full traceability from raw material to finished goods.
Why Choose Jinan Shenghe Chemical
Request a Quote
Looking for pricing, availability or technical data for Nebivolol?
Email us at sales@shenghechemical.com or use the button above. Our team typically responds within 1 business day.
About Jinan Shenghe Chemical Co., Ltd.
Jinan Shenghe Chemical Co., Ltd.
We are a professional chemical supplier based in Jinan, China. Since 2013, we have been connecting manufacturers and global B2B buyers with reliable sourcing, quality-controlled products and efficient logistics.
Our business covers food & feed additives, fine chemicals, pharmaceutical intermediates, eco-materials, coatings and specialty chemicals — all non-hazardous and compliant with our licensed scope.